Hi Friends.

We all know that Clozapine is least likely to cause EPS (Extra Pyramidal Side effects), and high potency typical antipsychotics are most likely to cause EPS among all antipsychotics.

Q1 (a) Which of the following antipsychotic is least likely to cause EPS.
Q1 (b) Which of the following antipsychotic is most likely to cause EPS.

(a) Risperidone
(b) Aripiprazole
(c) Olanzapine
(d) Quetiapine
(e) Ziprasidone

least likely to cause EPS- Seroquel
most likely- Abilify? akathisia or Risperidone

Answers:

Antipsychotic least likely to cause EPS: (d) Quetiapine

Antipsychotic most likely to cause EPS: (a) Risperidone

Antipsychotics Categories based on their tendencies to cause EPS:
(1) High potency typical antipsychotics- most likely to cause EPS
(2) Low potency typical antipsychotics
(3) Risperidone, Paliperidone
(4) Olanazpine, Ziprasidone, Aripiprazole
(5) Clozapine, Quetiapine- Least likely to cause EPS